Ethyl acetate extract of Wedelia chinensis inhibits tert-butyl hydroperoxide-induced damage in PC12 cells and D-galactose-induced neuronal cell loss in mice
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چکیده
منابع مشابه
Ethyl acetate extract of Wedelia chinensis inhibits tert-butyl hydroperoxide-induced damage in PC12 cells and D-galactose-induced neuronal cell loss in mice
BACKGROUND Wedelia chinensis is traditionally used as a hepatoprotective herb in Taiwan. The aim of this study was to evaluate the neuroprotective potential of W. chinensis. METHODS An ethyl acetate extract of W. chinensis (EAW) was prepared and analyzed by HPLC. The neuroprotective potential of EAW was assessed by tert-butylhydroperoxide (t-BHP)-induced damage in PC12 cells and D-galactose-i...
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Aims: Oxidative stress plays an important role in pathogenesis of seizure. In this study the effect of ethyl acetate fraction of Tanacetum parthenium against brain oxidative damage in pentylenetetrazole-induced (PTZ) seizure model in mice was investigated. Materials and methods: In this experimental study, mice were distributed into 6 groups: 1) Control, 2) PTZ, 3-6) Fraction+PTZ. The animals ...
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ژورنال
عنوان ژورنال: BMC Complementary and Alternative Medicine
سال: 2014
ISSN: 1472-6882
DOI: 10.1186/1472-6882-14-491